Take the Amtrak Southwest Chief from Chicago to La Plata. The train operates every day and is less than a 5 hour ride. If you are staying at the Depot Inn & Suites, call them in advance to arrange a free shuttle ride to the hotel. Click here if you'd like to purchase a book that is a route guide of everything you will see on your rail trip from Chicago to La Plata.
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Take the Amtrak Illinos Zephyr or Amtrak Carl Sandburg from Chicago to Quincy, Illinois. These two trains operate every day. If you are staying at the Depot Inn & Suites, be sure to call them several days in advance to ensure that their free shuttle service will be available on the day of your arrival.
Visit Amtrak.com to locate stations and trains near you that can take you to Chicago. From Chicago follow the above directions to continue to La Plata.
Take the eastbound Amtrak Southwest Chief to La Plata. From Los Angeles you will board in the evening, spend a night, a day, and another night on the train, then step off the train in La Plata in the morning. From other cities the rail trip will be shorter. La Plata is less than a 2 hour train trip from Kansas City. This train operates every day. If you are staying at the Depot Inn & Suites, call them in advance to arrange a free shuttle ride to the hotel.
Take the eastbound Amtrak California Zephyr to Ottumwa, Iowa. This train operates every day. If you are staying at the Depot Inn & Suites, be sure to call them several days in advance to ensure that their free shuttle service will be available on the day of your arrival.
From other cities, please check Amtrak.com for connections from the station nearest to you to La Plata, Missouri.
Cape Air offers several flights every day from St. Louis to the Kirksville Regional Airport. Click here for a schedule of flight times. Most major airlines provide direct or connecting flights from cities throughout United States and the world to St. Louis where you can connect to a flight to Kirksville. Baggage can usually be checked straight through from your point of origin to Kirksville. If you are staying at the Depot Inn & Suites, call them in advance to arrange a free shuttle ride to the hotel. The Depot Inn & Suites is only a 5 minute drive from the Kirksville Regional Airport.
Take I-70 West from St. Louis or I-70 East from Kansas City. From either city it is about a 2 hour, 120 mile drive, to Columbia, Missouri. From Columbia, head north on MO-63. La Plata is just a bit more than a one hour drive north on MO-63 from Columbia. From the MO-63 highway on your left you will see the Depot Inn & Suites and a sign for "D", short for Missouri State Highway "D".
Take I-80 West from Chicago to I-55. Take I-55 South to State Highway 36. Take 36 West to State Highway 63. Take 63 North to La Plata, Missouri. From the 63 highway on your left you will see the Depot Inn & Suites and a sign for "D", short for Missouri State Highway "D". Please check your GPS or online maps for shorter or faster routes from your origin in the Chicago area to La Plata, Missouri. The fastest route is 390 miles and about a 5 and one half hour drive without traffic.
Please use your GPS or online maps such as Google Maps for the shortest or fastest route to La Plata, Missouri.
Since the Depot Inn & Suites is a relatively new hotel, you will not find its exact address in some GPS and maps. Instead, set your GPS to navigate to the intersection of State Highway D & Amoco Rd in La Plata, MO. That will take you right to the hotel.
If you wish to rent a car, call the local Enterprise Rent-A-Car at 660-665-3396. They can have a car waiting for you 7 days per week at the Depot Inn & Suites, at the La Plata Amtrak Station, or at the Kirksville Airport, even if it is after hours and the Enterprise office is closed. You can also return your car after hours as long as you make arrangements with this Enterprise office in advance. Use Coupon Code L51EZ54 for significant savings. DO NOT CALL the nationwide toll free Enterprise phone number as they will not have any idea what you are talking about when you attempt to arrange after hours pick-up or drop-off service or attempt to use this coupon code.
The Depot Inn & Suites has an electric golf cart that guests may borrow to drive to the APRHF Rail Lookout Cabin & Deck. Many people walk from the hotel to the Rail Lookout but guests are welcome to use the golf cart if they'd rather not walk.